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. 2019 Jun 6;4(11):e126243. doi: 10.1172/jci.insight.126243

Figure 5. Transmission electron microscopy failed to demonstrate mature AFs along the dermal-epidermal junction of subject 5.

Figure 5

Thin sections of upper left arm control baseline (B), injected (I), and noninjected (NI) skin from subject 5 were obtained at 2 weeks, 3 months, and 12 months after treatment. No mature fan-shaped AFs were observed on any micrographs, but occasional thin wisp-like rudimentary AFs (black arrows) were visible at all time points. The epidermis was detached upon skin biopsy of the noninjected skin at month 12, and thus we were unable to obtain a meaningful intact dermal-epidermal junction transmission electron microscopy images. B, baseline; I, injected skin; M, month; NI, noninjected skin; W, week. Scale bar: 0.25 μm.