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. 2018 Mar 30;32(9):4941–4954. doi: 10.1096/fj.201701455RR

Figure 2.

Figure 2

Effect of fibroblast-specific p38α KO on ISO-induced cardiac dysfunction. A) Timeline for chronic β-adrenergic receptor activation model of cardiac hypertrophy. B) Individual representative PV loops obtained from control and fibroblast-specific p38α KO mice following infusion with either saline (control, blue) or ISO (red). C) PV conductance catheter data. Individual data and means ± sem are shown. Group sizes: control saline (n = 9), control ISO (n = 8), KO saline (n = 7), and KO ISO (n = 8). EDV, end diastolic volume; CO, cardiac output; SV, stroke volume. ANOVA with Sĭdák post hoc test: *P < 0.05, ***P < 0.001. NS, not significant.