TABLE 1.
Expression of miRNAs in control hearts
| miRNA | Expression (2−ΔCt) |
|---|---|
| 1a | 75.4 |
| 126a | 18.1 |
| 30c | 11.5 |
| 23a | 8.2 |
| 26a | 5.6 |
| 26b | 5.6 |
| 30a | 4.7 |
| 23b | 4.6 |
| 24 | 4.6 |
| 30e | 4.1 |
| 125b | 3.9 |
| 195a | 3.3 |
| 451a | 3.1 |
| 16 | 2.8 |
| 27a | 2.7 |
| let-7f | 2.7 |
| 378a | 2.7 |
| 21a | 2.6 |
| 30d | 2.5 |
| 125a | 2.1 |
| 29c | 2.1 |
| 29a | 2.0 |
Control (Cre-negative) mice were injected with tamoxifen and infused with saline, as described in Fig. 2A. Heart tissue was collected 1 wk after removal of miniosmotic pumps, and expression levels of 84 cardiovascular miRNAs were determined using a real-time RT-PCR array. Group sizes: n = 4. See Supplemental Table 1 for full data set. Table lists the 22 most highly expressed miRNAs in control hearts from saline-infused mice. Data are mean expression levels (2−ΔCt) relative to array-normalization controls.