Table 2. Risk factors associated with postpericardiotomy syndrome development in 58 patients referred for aortic valve surgery and/or thoracic aorta surgery.

Clinical characteristic		PPS		p value	HR (CI)
		Yes n=15	No n=43
Age (years), median (range)		65 (51)	69 (51)	0.055	1.136 (0.978-1.264)
Gender, n (%)	Male	8 (53)	29 (67)	0.328	0.552 (0.166-1.829)
	Female	7 (47)	14 (33)
NYHA ≥3, n (%)	Yes	13 (87)	34 (79)	0.506	1.721 (0.327-9.050)
	No	2 (13)	9 (21)
LVEF <50, n (%)	Yes	5 (33)	8 (19)	0.252	2.188 (0.584-8.189
	No	10 (67)	35 (81)
Coronary artery disease, n (%)	Yes	7 (47)	17 (39)	0.630	1.338 (0.409-4.374)
	No	8 (53)	26 (61)
Diabetes mellitus type 2, n (%)	Yes	3 (20)	11 (26)	0.659	0.727 (0.173-3.066)
	No	12 (80)	32 (74)
Chronic renal insufficiency, n (%)	Yes	3 (20)	7 (17)	0.746	1.286 (0.286-5.774)
	No	12 (80)	36 (83)
COPD, n (%)	Yes	1 (7)	2 (5)	0.767	1.464 (0.123-17.145)
	No	14 (93)	41 (95)
Urgent procedure, n (%)	Yes	2 (13)	0	0.018	0.867 (0.711-0.957)
	No	13 (87)	43 (100)
CABG, n (%)	Yes	4 (27)	10 (23)	0.521	1.2 (0.313-4.608)
	No	11 (73)	33 (77)
Mitral valve surgery, n (%)	Yes	0	2 (5)	0.546	1.049 (0.982-1.120)
	No	15 (100)	41 (95)
Fever postoperative, n (%)	Yes	4 (27)	1 (3)	0.013	15.273 (1.547-150.765)
	No	11 (73)	42 (97)
CRP >5 mg/L, n (%)	Yes	13 (87)	15 (35)	0.001	12.133 (2.412-61.029)
	No	2 (13)	28 (65)
Antibiotic postoperative, n (%)	Yes	7 (47)	5 (12)	0.004	6.650 (1.677-26.357)
	No	8 (53)	38 (88)

PPS = postpericardiotomy syndrome; NYHA = New York Heart Association functional classification; LVEF = left ventricular ejection fraction; COPD = chronic obstructive pulmonary disease; CABG = coronary artery bypass graft; CRP = C-reactive protein