Skip to main content
. 2019 Jul 11;4(13):e126241. doi: 10.1172/jci.insight.126241

Figure 1. Relationship between a high-salt diet and the human gut microbiome.

Figure 1

(A) Study design; self-reported dietary Na+ intake was estimated from Food Frequency Questionnaires for 12 months (long-term) and 3-day food records prior to the study visit (short-term). 16S rRNA analysis was performed on fecal samples. (B) Rarefaction curve of OTUs in fecal samples. (C) α Diversity measure in people eating a normal salt diet versus a high-salt diet. (D) β Diversity measure in normal versus high salt. (E) Nonmetric multidimensional scaling (NMDS) of bacteria from people eating a low- versus high-salt diet. (F) Relative abundance of selected 16S rRNA gene targets with microbial primers for all taxa. (G) Relative abundance of selected 16S rRNA gene targets with given microbial primers of the 50 most abundant taxa. 16S rRNA data analyses were performed using R software and a type-I error rate of 0.05 was set to infer statistical significance.