Skip to main content
. 2019 Jul 11;4(13):e126241. doi: 10.1172/jci.insight.126241

Figure 5. A high-salt diet alters the gut microbiome in mice.

Figure 5

(A) Experimental design; cecal samples from C57BL/6 mice fed a high-salt diet for 3 weeks and regular diet (normal salt) were subjected to 16S rRNA analysis. (B) Body weight of normal salt diet– and high-salt diet–fed mice. (C) Species biodiversity estimation in cecal samples of normal salt diet– and high-salt diet–fed mice. (D) Relative abundance of selected 16S rRNA gene targets with microbial primers for all taxa. (E) Relative abundance of selected 16S rRNA gene targets with given microbial primers of the 50 most abundant taxa. (F) Nonmetric multidimensional scaling (NMDS) showing that the bacteria from normal salt (NS) and high-salt (HS) diet–fed mice cluster separately. Effect of a high-salt diet on the phyla Firmicutes (G) and Bacteroidetes (H). (I) Effect of a high-salt diet on the Firmicutes/Bacteroidetes ratio (***P < 0.0001, n = 10 normal salt and n = 9 high salt using 2-tailed unpaired Student’s t tests).