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. 2019 Jul 11;4(13):e128014. doi: 10.1172/jci.insight.128014

Figure 3. Intragraft abundance of mRNAs encoding cytokines, chemokines, IFNs, and TNF in human kidney allograft biopsies.

Figure 3

mRNA abundance of cytokines (A), chemokines (B), IFNs and TNF (C) in TCMR and Normal. Signaling through the PRRs results in the activation of NF-κB, IFN regulatory factors, and NFATC transcription factors, which together with caspases trigger the expression of cytokines, chemokines, IFNs, and TNF.