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Dl-NBP improves the activities of PMCA and Na/K-ATPase in the mitochondrion. NBP might act directly on mitochondrial complex IV to increase its activity. dl-NBP: dl-3-N-butylphthalide; NBP: 3-N-butylphthalide; PMCA: Plasma membrane Ca2+-ATPase; PGI2: prostaglandin I2; ADP: Adenosine diphosphate; ATP: Adenosine triphosphate.
