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. 2019 Jun 5;132(11):1298–1304. doi: 10.1097/CM9.0000000000000243

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Copyright © 2019 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

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Effects of TFEB on the inflammatory factors in the cell supernatant (A–C) and in the BALF (D–F). The overexpression of TFEB could reduce the expression of IL-1 and IL-6 and increase the expression of IL-10. The knockdown of TFEB expression could increase the expression of IL-1 and IL-6 and reduce the expression of IL-10. Data are presented as the mean ± SEM (n = 3 for the cell supernatant, and n = 5 for the BALF). ^∗P < 0.05 vs. control group; ^†P < 0.05 vs. LPS group. BALF: Bronchoalveolar lavage fluid; LPS: Lipopolysaccharide; TFEB: Transcription factor EB.