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. 2019 Jun 5;132(11):1344–1353. doi: 10.1097/CM9.0000000000000232

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Copyright © 2019 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

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Expression of tight junction proteins in BMECs analyzed by Western blotting. (A) Protein level of claudin-5, ZO-1, and occludin detected by Western blotting in the hypoxia model and the densitometric analysis of protein expression (n = 6). (B) Protein level of claudin-5, ZO-1, and occludin detected by Western blotting in the OGD/R model and densitometric analysis of protein expression (n = 6). ^∗P < 0.01 vs. the control group; ^†P < 0.05 vs. the hypoxia group or OGD/R group. ^‡P < 0.01 vs. the hypoxia group or OGD/R group. BMECs: Brain microvascular endothelial cells; OGD/R: Oxygen-glucose deprivation/reoxygenation; ZO-1: Zonula occludens-1.