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NBP attenuated ROS generation induced by hypoxia in rat BMECs. (A) Representative micrographs of ROS generation (under fluorescence microscope). Scale bar = 200 μm. (B) ROS generation measured by flow cytometry (n = 6). ∗P < 0.01 vs. the control group; †P < 0.01 vs. the hypoxia group; ‡P < 0.01 vs. NBP (0.1 μmol/L) group. BMECs: Brain microvascular endothelial cells; NBP: DL-3-n-butylphthalide; ROS: Reactive oxygen species.
