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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2019 Jul;43(7):885–897. doi: 10.1097/PAS.0000000000001252

Figure 2: Carcinomas with Mucoepidermoid Morphology.

Figure 2:

Most (81%) carcinomas reviewed were morphologically compatible with MEC. Solid growth was the most common reason for assigning Brandwein intermediate grade, as seen in this well-circumscribed (A) mucoepidermoid carcinoma with intermediate cells, glycogenated cells (B), rare mucinous cells, and MAML2 rearrangement (B, inset). Occasional carcinomas morphologically consistent with MEC (C), showed intermediate cells, squamoid cells, and mucinous cells (D) but lacked MAML2 rearrangement. A true high grade mucoepidermoid carcinoma also showed appropriate cell types and high grade features, including perineural invasion (E, inset), rare mucinous cells (F, top inset), and MAML2 rearrangement (F, bottom inset).