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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2019 Jul;43(7):885–897. doi: 10.1097/PAS.0000000000001252

Figure 3: Carcinomas of Non-Mucoepidermoid Morphology.

Figure 3:

Some carcinomas (19%) originally diagnosed as MEC by the signout pathologist were not compatible with MEC upon contemporary review. This primary palate carcinoma showed micropapillary architecture (A) with extracellular mucin pools (B) and was negative for MAML2 rearrangement, suggestive of the rare mucinous adenocarcinoma. A buccal carcinoma demonstrated abundant eosinophilic hyalinized stroma (C) and a single cell type with clear cytoplasm and wrinkled nuclei (D), consistent with clear cell carcinoma. Another palate carcinoma also showed a single cell type with single-file infiltration within fibrous stroma (E) and perineural invasion (F). The remaining non-MEC cases were not morphologically specific for other salivary type carcinomas.