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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Semin Nephrol. 2019 Jul;39(4):353–367. doi: 10.1016/j.semnephrol.2019.04.005

TABLE I. Relevant Proteins Expressed in Kidney Intercalated Cells (adapted from (74)).

The differential localization patterns pertaining to the transport proteins listed in bold and italics identify a combination of key markers that aid in the classification of the different intercalated cell subtypes.

Intercalated Cell Type Type A Type B Non-A, non-B
Protein Expressed
Carbonic anhydrase II apical cytoplasmic cytoplasmic
V-ATPase apical basolateral apical and diffuse vesicular
AE1 basolateral
c-Kit basolateral
Pendrin (Slc26a4) apical apical
H+,K+-ATPase apical apical ?
AE4 basolateral
RhBG basolateral basolateral
RhCG apical apical
NDCBE (Slc4a8) apical
Slc4a11 apical