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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Curr Opin Neurobiol. 2019 Jan 30;57:32–38. doi: 10.1016/j.conb.2018.12.014

Figure 1. Neurovascular unit and transcytosis at the BBB.

Figure 1

(A) Cross-section of the neurovascular unit depicting endothelial cells surrounded by pericytes and astrocytes on their abluminal side. (B) Schematic illustrating the two kinds of transcytosis in CNS endothelial cells: molecules with specific receptors on CNS endothelial cells such as insulin and transferrin undergo receptor-mediated transcytosis while molecules such as albumin get endocytosed through charged interactions and undergo adsorptive transcytosis.