Table 1. Patient characteristics and liver MRI information for the overall cohort and according to presence of non-diagnostic MRE.
| Variable | All patients (N=95) | Non-diagnostic elastography (N=32) | Adequate elastography (N=63) | P value |
|---|---|---|---|---|
| Patient characteristics | ||||
| Age at elastography (years) | 57 (31, 84) | 56 (34, 84) | 58 (31, 81) | 0.92 |
| Sex (male) | 67 (70.5%) | 21 (65.6%) | 46 (73.0%) | 0.48 |
| Race (White) | 81 (87.1%) | 23 (74.2%) | 58 (93.5%) | 0.018 |
| Weigh (kg) | 85.0 (48.0, 136.0) | 80.2 (50.9, 136.0) | 88.5 (48.0, 127.0) | 0.018 |
| BMI | 26.6 (18.3, 45.1) | 25.1 (18.6, 41.2) | 27.0 (18.3, 45.1) | 0.068 |
| Hereditary hemochromatosis | 64 (67.4%) | 17 (53.1%) | 47 (74.6%) | 0.041 |
| Diabetes | 29 (30.5%) | 12 (37.5%) | 17 (27.0%) | 0.35 |
| Chronic kidney disease | 24 (25.3%) | 12 (37.5%) | 12 (19.0%) | 0.079 |
| Anemia | 19 (20.0%) | 11 (34.4%) | 8 (12.7%) | 0.016 |
| History of iron overload | 69 (72.6%) | 27 (84.4%) | 42 (66.7%) | 0.089 |
| Family history of iron overload | 9 (9.6%) | 1 (3.2%) | 8 (12.7%) | 0.26 |
| History of alcohol use | 43 (45.3%) | 17 (53.1%) | 26 (41.3%) | 0.29 |
| Number of drinks per week | 0.21 | |||
| None | 52 (56.5%) | 15 (50.0%) | 37 (59.7%) | |
| Up to 7 | 27 (29.3%) | 8 (26.7%) | 19 (30.6%) | |
| 7 to 14 | 10 (10.9%) | 5 (16.7%) | 5 (8.1%) | |
| More than 14 | 3 (3.3%) | 2 (6.7%) | 1 (1.6%) | |
| Liver MRI information | ||||
| HCC | 1 (1.1%) | 1 (3.1%) | 0 (0.0%) | 0.34 |
| Iron overload | 54 (57.4%) | 30 (93.8%) | 24 (38.7%) | <0.0001 |
| Hepatic steatosis | 6 (6.5%) | 1 (3.2%) | 5 (8.2%) | 0.66 |
| Cirrhotic morphology | 13 (14.0%) | 3 (9.7%) | 10 (16.1%) | 0.53 |
| MRE value (kPa) | 2.4 (1.5, 6.7) | N/A | 2.4 (1.5, 6.7) | N/A |
| Liver lesion | 10 (10.6%) | 6 (18.8%) | 4 (6.5%) | 0.084 |
| Fat | 5 (5.4%) | 1 (3.2%) | 4 (6.6%) | 0.66 |
| T2* (ms) | 16.0 (2.6, 41.0) | 6.0 (3.0, 18.0) | 22.0 (2.6, 41.0) | <0.0001 |
The sample median (minimum, maximum) is given for continuous variables. P values result from Fisher’s exact test or a Wilcoxon rank sum test comparing variables between patients with non-diagnostic elastography and adequate elastography. Information was unavailable regarding race (N=2), family history of iron overload (N=1), number of drinks per week (N=3), HCC (N=1), iron overload from liver MRI (N=1), hepatic steatosis (N=3), cirrhotic morphology (N=2), MRE value (N=2), liver lesion (N=1), and fat (N=3). MRE, magnetic resonance elastography; BMI, body mass index; N/A, not available.