Table 2. Effect of histopathological features on 3D ME Dixon parameters: univariate and multiple regression analyses.
| Variables | Univariate analysis | Multiple regression analysis | ||||
|---|---|---|---|---|---|---|
| r | P | R2 | β | P | ||
| MRI-PDFF | ||||||
| Steatosis | 0.858 | <0.001 | 0.803 | 0.896 | <0.001 | |
| Iron overload | −0.219 | 0.031 | − | − | − | |
| Fibrosis | −0.015 | 0.884 | − | − | − | |
| Inflammation | 0.304 | 0.002 | − | − | − | |
| ALT level | 0.046 | 0.53 | − | − | − | |
| AST level | −0.015 | 0.886 | − | − | − | |
| TBIL level | −0.001 | 0.994 | − | − | − | |
| R2* value | ||||||
| Steatosis | −0.072 | 0.481 | − | − | − | |
| Iron overload | 0.743 | <0.001 | 0.647 | 0.767 | <0.001 | |
| Fibrosis | 0.366 | <0.001 | 0.647 | 0.13 | <0.001 | |
| Inflammation | 0.211 | 0.036 | − | − | − | |
| ALT level | 0.035 | 0.735 | − | − | − | |
| AST level | −0.013 | 0.898 | − | − | − | |
| TBIL level | 0.035 | 0.734 | − | − | − | |
PDFF, proton density fat fraction; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin.