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. 2019 Jul 12;20:100487. doi: 10.1016/j.ymgmr.2019.100487

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© 2019 Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Spirometry changes over the course of the study.

The diagram illustrates individual plots and natural progression in spirometry for each subject, along with summary plots, divided into ERT and non-ERT groups. This was conducted for each of the following spirometry variables: (A) FEV₁, (B) FEV₁[%Pred], (C) FVC, (D) FVC [%Pred], (E) FEV₁/FVC) and (F) 6MWT. Note, when values are averaged out for both the ERT and non-ERT group, there is global decline in spirometry values over the course of the study.

Fig. 2 — Spirometry changes over the course of the study.

The diagram illustrates individual plots and natural progression in spirometry for each subject, along with summary plots, divided into ERT and non-ERT groups. This was conducted for each of the following spirometry variables: (A) FEV₁, (B) FEV₁[%Pred], (C) FVC, (D) FVC [%Pred], (E) FEV₁/FVC) and (F) 6MWT. Note, when values are averaged out for both the ERT and non-ERT group, there is global decline in spirometry values over the course of the study.