Table 3. Correlation between clinical parameters and inflammatory biomarkers.
Inflammatory biomarker | Fever, ≥38°C | Bloody diarrhea | Bacterial pathogen | Viral pathogen | |
---|---|---|---|---|---|
Blood | |||||
CRP (mg/L) | <0.001* | 0.98 | <0.001* | 0.64 | |
ESR (mm/hr) | 0.05 | 0.19 | 0.04† | 0.32 | |
Leukocytes (/µL) | 0.57 | 0.58 | 0.54 | 0.40 | |
Fecal | |||||
Calprotectin (µg/g) | 0.69 | 0.12 | 0.03† | 0.61 | |
Lactoferrin (µg/mL) | 0.38 | 0.34 | 0.003‡ | 0.22 | |
MPO (ng/mL) | 0.35 | 0.25 | 0.02† | 0.53 | |
PMN-e (µg/mL) | 0.96 | 0.09 | 0.05 | 0.33 | |
Leukocyte, positive | 0.17 | 0.52 | 0.03† | 1.00 | |
Occult blood, positive | 0.77 | 0.02† | 0.002‡ | 0.78 |
CRP: C-reactive protein, ESR: erythrocyte sedimentation rate, MPO: myeloperoxidase, PMN-e: polymorphonuclear elastase.
p-values were calculated by Mann-Whitney test or Fisher's exact test; *p<0.001, †p<0.05, ‡p<0.01.