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. 2019 Jul 15;9:10227. doi: 10.1038/s41598-019-46734-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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General cell-cycle model highlighting the genes that respond to Ustilago maydis infection. Cell cycle consist of four phases: G1, S, G2 and M. S-phase (Synthesis) is where DNA replication takes place, and M-phase (Mitosis), where nuclear division occurs. G1 and G2 are gap phases where some checkpoints to control cell cycle progression take place. A more detailed explanation of the cycle is given in the text. Genes differentially regulated (|log2FC| ≥ 1.5) are shown. Circles at the beginning of S-phase and middle of G2 and mitosis represent cell-cycle progression checkpoints. Colors represent gene expression profile: red = upregulated and blue = downregulated.