Table 1.
Patient group characteristics.
| Cyst fluid (n = 31) | Plasma (n = 21) | |||||||
|---|---|---|---|---|---|---|---|---|
| SCN | IPMN | SCN | IPMN | |||||
| LGD | HGD | Cancer | LGD | HGD | Cancer | |||
| Patients, % (n) | 16.1 (5) | 25.8 (8) | 22.6 (7) | 35.5 (11) | 23.8 (5) | 23.8 (5) | 28.6 (6) | 23.8 (5) |
| Female, % | 100 | 50* | 42.9* | 27.3** | 100 | 20* | 33.3* | 40 |
| Alcohol use, % | 60 | 25 | 28.6 | 18.2 | 40 | 20 | 16. 7 | 60 |
| Smokers, % | 40 | 0 | 0 | 9.1 | 40 | 0 | 0 | 40 |
| CVD, % | 20 | 71.4 | 71.4 | 54.6 | 20 | 60 | 50 | 60 |
| Statins use, % | 20 | 12.5 | 14.3 | 9.09 | 20 | 0 | 16.7 | 40 |
| Diabetes, % | 0 | 12.5 | 42.9 | 36.4 | 0 | 20 | 16.7 | 20 |
| Age, years | 48 | 66** | 72*** | 69*** | 53 | 65 | 72.5** | 69** |
| median (range) | (34–58) | (56–81) | (66–75) | (46–83) | (34–68) | (56–76) | (66–75) | (65–83) |
| BMI, kg/m2 | 29.64 | 27.51 | 27.21 | 24.97 | 28.01 | 32.16 | 24 | 25.69 |
| median (range) | (24.1–32.0) | (21.8–36.6) | (23.4–28.3) | (20.2–29.7) | (24.1–31.0) | (24.8–36.6) | (21.5–28.3) | (24.1–32.9) |
| HbA1c, mmol/mol | 31 | 42.5 | 38 | 43* | 33 | 44 | 38 | 51.5 |
| median (range) | (30–37) | (35–48) | (31–55) | (31–67) | (30–43) | (37–48) | (31–55) | (31–81) |
| S-CA 19–9, kE/L | 11 | 18 | 11 | 376* | 11 | 11 | 16 | 285** |
| median (range) | (6.8–62) | (6.4–182) | (<1–115) | (<1–1040) | (7.9–62) | (6.4–182) | (<1–115) | (46–480) |
| Serum amylase, µkat/L | 0.3 | 0.41 | 0.24 | 0.25 | 0.31 | 0.44 | 0.195 | 0.27 |
| median (range) | (0.19–1.64) | (<0.13–0.65) | (<0.13–0.93) | (<0.13–0.87) | (0.19–1.64) | (<0.13–0.54) | (<0.13–0.72) | (<0.13–0.54) |
| Albumin, g/L | 36 | 36 | 36 | 31 | 38 | 37 | 34.5 | 31.5 |
| median (range) | (33–39) | (26–38) | (22–39) | (19–38) | (33–39) | (36–39) | (22–39) | (28–34) |
| Bilirubin, µmol/L | 6 | 6.5 | 5 | 24 | 6 | 8 | 8 | 30 |
| median (range) | (3–18) | (<3–13) | (<3–315) | (5–150) | (3–7) | (4–13) | (4–315) | (12–119) |
| WBC, × 109/L | 6.3 | 7.45 | 7.8 | 9.8 | 6.3 | 7.5 | 8.3 | 11.2** |
| median (range) | (4.4–9.2) | (5–9.4) | (5.6–12.9) | (5–13.9) | (4.4–9.2) | (5.3–9.4) | (7.2–12.9) | (8–13.9) |
Statistical comparisons between each group and the control group (SCN) were made using one-way ANOVA with Dunnett’s multiple comparisons test for quantitative parameters and chi-square test for qualitative values; *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001.