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. 2019 Jul 1;26(7):624–635. doi: 10.5551/jat.43968

Table 6. Estimate mean value (95% CI) for the association between sdLDL-C and cardiovascular biomarkers in participants without CAD excluded current smokers (n = 489).

sdLDL-C, mg/dL
< 21.0 21.0–29.7 29.8–42.4 > 42.4 p-valueb
n = 150 n = 149 n = 147 n = 148
hs-CRP, mg/dL 0.13 (0.11, 0.14) 0.15 (0.13, 0.16) 0.15 (0.14, 0.16) 0.27 (0.23, 0.30) 0.0142
White blood cells, 103/µL 5.62 (5.52, 5.72) 5.92 (5.78, 6.06) 5.89 (5.83, 5.96) 6.58 (6.46, 6.70) < 0.0001
Neutrophils,103/µL 3.18 (3.12, 3.24) 3.38 (3.29, 3.47) 3.31 (3.26, 3.36) 3.80 (3.71, 3.89) 0.0003
Lymphocytes, 103/µL 1.94 (1.90, 1.97) 2.06 (2.01, 2.10) 2.07 (2.04, 2.10) 2.21 (2.17, 2.25)* 0.0004
Monocytes, 103/µL 0.276 (0.273, 0.279) 0.306 (0.299, 0.314) 0.285 (0.279, 0.290) 0.316 (0.308, 0.323) 0.0509
Fibrinogen, mg/dL 256.9 (254.6, 259.1) 264.0 (261.0, 267.1) 262.1 (260.2, 264.1) 276.1 (272.9, 279.3)* 0.004
D-dimer, mg/L 0.324 (0.316, 0.332) 0.309 (0.306, 0.313) 0.359 (0.329, 0.389) 0.30 (0.284, 0.316) 0.9891
Adiponectin, ng/mL 2573.0 (2354, 2792) 1993.5 (1861, 2126) 1888.1 (1714, 2063)* 1467.2 (1394, 1540) < 0.0001
Glu AUC ,mg/dL 218.8 (214.7, 223.0) 234.8 (231.8, 237.8) 254.1 (250.4, 257.8) 282.0 (277.6, 286.5) < 0.0001
Hemoglobin A1c, % 5.48 (5.45, 5.52) 5.53 (5.51, 5.55) 5.54 (5.52, 5.56) 5.95 (5.90, 6.00) < 0.0001
Red blood cells, 106/µL 5.03 (4.99, 5.07) 5.24 (5.18, 5.30)* 5.18 (5.15, 5.21) 5.26 (5.23, 5.29) 0.0086
Hematocrit,% 44.54 (44.20, 44.88) 45.59 (45.23, 45.95) 45.92 (45.69, 46.15)* 46.53 (46.29, 46.78) < 0.0001
a

Data in tables were derived from the least square mean (95% CI) after adjusting for age, gender, BMI, hypertension, household income, smoking and drinking habits.

Significance in asterisk of quartiles 2, 3, 4 indicate p-value compared with quartile 1 after multiple linear regression analyses.

b

p-value for trend were modeled according to median value of each quartile.

*

p < 0.05,

p < 0.01,

p < 0.001

Abbreviations: hs-CRP, high-sensitivity C-reactive protein; Glu AUC, glucose levels area under curve after OGTT