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. 2019 Jul 1;26(7):636–658. doi: 10.5551/jat.45963

Table 1. The top five results of functional enrichment analyses of up-regulated DEGs ranked by P-value.

Term Count Gene P-value
GO-BPs
    GO:0006955∼immune response 9 PPBP, IGKV1-17, CXCL3, NCF4, FCGR3A, IGKC, HLA-DMA, IGLC1, CD27 4.82E-05
    GO:0050853∼B cell receptor signaling pathway 4 CD38, IGKC, IGHM, IGLC1 6.57E-04
    GO:0038096∼Fc-gamma receptor signaling pathway involved in phagocytosis 5 IGKV1-17, HCK, FCGR3A, IGKC, IGLC1 6.86E-04
    GO:0006954∼inflammatory response 7 PPBP, CXCL3, HCK, S100A9, MGLL, CD27, CD180 0.001192
    GO:0050776∼regulation of immune response 5 LAIR1, IGKV1-17, FCGR3A, IGKC, IGLC1 0.002385
KEGG pathways
    hsa04142:Lysosome 6 AP1B1, GLA, GAA, NEU1, CTSA, ATP6V0B 1.08E-04
    hsa04060:Cytokine-cytokine receptor interaction 5 LEP, PPBP, IL10RA, TNFRSF17, CD27 0.013065
    hsa04145:Phagosome 4 NCF4, FCGR3A, HLA-DMA, ATP6V0B 0.023255
    hsa03320:PPAR signaling pathway 3 CYP27A1, FABP4, PLTP 0.02977
    hsa05140:Leishmaniasis 3 NCF4, FCGR3A, HLA-DMA 0.033129

GO, Gene Ontology; BP, biological process; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes.