Table 1. The top five results of functional enrichment analyses of up-regulated DEGs ranked by P-value.
Term | Count | Gene | P-value |
---|---|---|---|
GO-BPs | |||
GO:0006955∼immune response | 9 | PPBP, IGKV1-17, CXCL3, NCF4, FCGR3A, IGKC, HLA-DMA, IGLC1, CD27 | 4.82E-05 |
GO:0050853∼B cell receptor signaling pathway | 4 | CD38, IGKC, IGHM, IGLC1 | 6.57E-04 |
GO:0038096∼Fc-gamma receptor signaling pathway involved in phagocytosis | 5 | IGKV1-17, HCK, FCGR3A, IGKC, IGLC1 | 6.86E-04 |
GO:0006954∼inflammatory response | 7 | PPBP, CXCL3, HCK, S100A9, MGLL, CD27, CD180 | 0.001192 |
GO:0050776∼regulation of immune response | 5 | LAIR1, IGKV1-17, FCGR3A, IGKC, IGLC1 | 0.002385 |
KEGG pathways | |||
hsa04142:Lysosome | 6 | AP1B1, GLA, GAA, NEU1, CTSA, ATP6V0B | 1.08E-04 |
hsa04060:Cytokine-cytokine receptor interaction | 5 | LEP, PPBP, IL10RA, TNFRSF17, CD27 | 0.013065 |
hsa04145:Phagosome | 4 | NCF4, FCGR3A, HLA-DMA, ATP6V0B | 0.023255 |
hsa03320:PPAR signaling pathway | 3 | CYP27A1, FABP4, PLTP | 0.02977 |
hsa05140:Leishmaniasis | 3 | NCF4, FCGR3A, HLA-DMA | 0.033129 |
GO, Gene Ontology; BP, biological process; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes.