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. 2019 Jul 9;10:459. doi: 10.3389/fendo.2019.00459

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Copyright © 2019 Huang, Xu, Wu, Chen, Bai, Zhuang, Fang and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathological morphological features of kidney tissues in each group of rats. (A) Pathological morphological features of glomeruli in each group of rats. The arrow shows mesangial hyperplasia. (B) Mesangial index of rats in each group. (C) Pathological morphological features of renal tubules in each group. The arrow shows the protein-like cast. (D) Tube area percentage of each group of rats. (E) Pathological morphological features of renal arterioles in each group. The arrow shows thickening of the arteriolar wall. (F) Renal arteriosclerosis index of rats in each group. Data are presented as mean ± SD. n = 8. *P < 0.05 vs. Control, #P < 0.05 vs. DM group.