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. 2019 Jul 9;13:587. doi: 10.3389/fnins.2019.00587

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Copyright © 2019 Sorby-Adams, Leonard, Elms, Marian, Hoving, Yassi, Vink, Thornton and Turner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Temporal profile of ICP following transient MCAO. ICP was significantly elevated at 5 days (p < 0.001) and 6 days (p < 0.05) post-stroke when compared to sham. By 7 days, ICP began to resolve though remained elevated compared to sham (p < 0.05). ^∗∗∗∗p < 0.0001; and ^∗∗∗p < 0.001 compared to sham. n = 6/time-point, n = 4 sham.