Table 1.
Demographics and sleep characteristics (subjective, AASM-based, and LDA model-based) in ID and controls.
| Controls | ID | P | |
|---|---|---|---|
| Demographics | |||
| N | 64 | 55 | - |
| Age [years, μ ± σ] | 45.3 ± 14.6 | 47.8 ± 12.9 | 0.41 |
| Sex [male/female] | 22/42 | 14/41 | 0.29 |
| Subjective insomnia | |||
| ISI [μ ± σ] | 3.8 ± 3.7 | 16.5 ± 4.3 | <0.0001 |
| AASM-based measures | |||
| TiB [min, μ ± σ] | 483.3 ± 52.7 | 471.6 ± 44.5 | 0.10 |
| TST [min, μ ± σ] | 421.7 ± 60.7 | 400.6 ± 59.3 | 0.03 |
| SE [%, μ ± σ] | 87.3 ± 8.6 | 85.1 ± 10.7 | 0.32 |
| Wake [%, μ ± σ] | 11.7 ± 8.7 | 14.3 ± 10.9 | 0.23 |
| REM [%, μ ± σ] | 20.2 ± 6.7 | 19.4 ± 8.5 | 0.45 |
| N1 [%, μ ± σ] | 3.6 ± 2.4 | 5.0 ± 4.1 | 0.13 |
| N2 [%, μ ± σ] | 39.9 ± 9.4 | 37.8 ± 11.1 | 0.12 |
| N3 [%, μ ± σ] | 23.6 ± 9.0 | 22.9 ± 10.2 | 0.62 |
| LDA model-based overall average topic probability | |||
| T1 [%, μ ± σ] | 5.69 ± 1.67 | 5.23 ± 1.50 | 0.23 |
| T2 [%, μ ± σ] | 25.06 ± 2.64 | 24.86 ± 2.65 | 0.52 |
| T3 [%, μ ± σ] | 31.08 ± 3.14 | 31.70 ± 2.77 | 0.44 |
| T4 [%, μ ± σ] | 12.81 ± 1.43 | 13.08 ± 1.38 | 0.26 |
| T5 [%, μ ± σ] | 18.97 ± 2.88 | 18.76 ± 2.63 | 0.94 |
| T6 [%, μ ± σ] | 5.62 ± 1.66 | 5.59 ± 1.42 | 0.56 |
| LDA model-based percentage of time of stable epochs for each stable epoch type and in total (for the subset of participants with a non-zero number of stable epochs) | |||
| Stable T1 epochs [%, μ ± σ] (number of subjects expressing non-zero values) | 1.51 ± 2.09 (NC = 30) | 1.11 ± 1.24 (NID = 22) | 0.57 |
| Stable T2 epochs [%, μ ± σ] (number of subjects expressing non-zero values) | 19.98 ± 4.71 (NC = 64) | 20.01 ± 4.51 (NID = 55) | 0.94 |
| Stable T3 epochs [%, μ ± σ] (number of subjects expressing non-zero values) | 24.33 ± 6.04 (NC = 64) | 24.72 ± 5.38 (NID = 55) | 0.98 |
| Stable T4 epochs [%, μ ± σ] (number of subjects expressing non-zero values) | 2.73 ± 2.44 (NC = 62) | 3.42 ± 2.83 (NID = 55) | 0.24 |
| Stable T5 epochs [%, μ ± σ] (number of subjects expressing non-zero values) | 7.33 ± 4.43 (NC = 64) | 7.67 ± 4.54 (NID = 55) | 0.46 |
| Stable T6 epochs [%, μ ± σ] (number of subjects expressing non-zero values) | 1.59 ± 1.94 (NC = 44) | 1.06 ± 1.26 (NID = 37) | 0.34 |
| Stable epochs in total [%, μ ± σ] (number of subjects expressing non-zero values) | 56.08 ± 5.42 (NC = 64) | 57.29 ± 6.59 (NID = 55) | 0.23 |
The P-value for the statistics on sex is obtained from a Chi-square test. All other P-values were obtained from Wilcoxon rank sum tests. Bold font-style indicates significant group differences. ID, insomnia disorder; ISI, insomnia severity index; TiB, time in bed from lights out time to get up time; TST, total sleep time; SE, sleep efficiency; T1-T6, topic 1 to 6; LDA, latent Dirichlet allocation.