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. 2019 Jul 16;39(7):BSR20181722. doi: 10.1042/BSR20181722

Figure 5. miR-130a inhibited the expression of PPARγ by binding with its 3′-UTR.

Figure 5

Relative expression level of miR-130a (A) and PPARγ (B) was measured by qRT-PCR in HepG2 and Huh-7 cells transfected with miR-130a mimics and inhibitor. (C) Predicted binding site between miR-130a and PPARγ by TargetScan software. (D) The luciferase activity of the PPARγ-WT and PPARγ-MUT in HepG2 and Huh-7 cells transfected with miR-130a mimics and inhibitor. All the results were shown as mean ± SD (n=3), which were three separate experiments performed in triplicate. *P<0.05 and **P<0.01.