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The density distributions of residues groups' RMSDs in apo (green dot dashed line), reactant (red dashed line) and product (blue dot line) states: (A) RMSD of Ω loop (residues 163–180), (B) RMSD of residues 213–220, (C) RMSD of helix 12 (residues 272–288), (D) RMSD of residues 102–108.
