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. 2019 Jul 9;10:759. doi: 10.3389/fphar.2019.00759

Table 5.

Common mechanisms and effects observed in skin aging (↑) and in damage skin after air pollution exposition (▲).

Mechanisms Biological effects Effects on the skin
Aging/pollutants Aging/pollutants Aging/pollutants
Activation of AhR ↑/▲ Increase of melanogenesis ↑/▲ Hyperpigmentation ↑/▲
Generation of ROS ↑/▲ DNA damage.
Lipid peroxidation.
↑/▲ Wrinkles ↑/▲
Induction of inflammatory cascade ↑/▲ Decrease
collagen
↑/▲ Delayed healing skin ↑/▲
Disruption of skin barrier ↑/▲ Increase MMPs ↑/▲ Dry skin ↑/▲
Exacerbation of skin diseases ↑/▲