Table 5.
Mechanisms | Biological effects | Effects on the skin | |||
---|---|---|---|---|---|
Aging/pollutants | Aging/pollutants | Aging/pollutants | |||
Activation of AhR | ↑/▲ | Increase of melanogenesis | ↑/▲ | Hyperpigmentation | ↑/▲ |
Generation of ROS | ↑/▲ | DNA damage. Lipid peroxidation. |
↑/▲ | Wrinkles | ↑/▲ |
Induction of inflammatory cascade | ↑/▲ | Decrease collagen |
↑/▲ | Delayed healing skin | ↑/▲ |
Disruption of skin barrier | ↑/▲ | Increase MMPs | ↑/▲ | Dry skin | ↑/▲ |
Exacerbation of skin diseases | ↑/▲ |