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. 2019 May 15;25(8):832–841. doi: 10.1111/cns.13113

Figure 3.

Figure 3

Fos protein expression induced by acute stress and ciproxifan after CSD task. Upper part. Representative photomicrographs of Fos immunopositive neurons in the PL, the CA1 of the hippocampus and the BLA of the amygdala (magnification ×20; scale bar: 100 µm). Lower part. Fos positive cell number are expressed by mean + SEM relative to naive animal level for prefrontal cortex (IL = infralimbic cortex; PrL = prelimbic cortex; A) dorsal hippocampus (CA1; CA3 for cornu ammonis; DG = dentate gyrus; B) and amygdala (LA = lateral amygdala; BLA = basolateral amygdala; CeA = central amygdala; C). Mean were calculated from three representative brain slices for vehicle (Veh) and ciproxifan 3 mg/kg (Cipro3) groups. Stress effect (unpaired t test): *P < 0.05, **P < 0.01, ***P < 0.001. Ciproxifan effect (unpaired t test): •P < 0.05. The numbers of mice per group are: Il (11, 8, 12, 10), PrL (11, 8, 12, 10), Hippocampus (12, 13, 15, 13), Amygdala (12, 9, 13, 11) for Vehicle Nonstress, Ciproxifan Nonstress, Vehicle Stress and Ciproxifan Stress respectively.