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. 2019 Jul 9;13:701. doi: 10.3389/fnins.2019.00701

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Copyright © 2019 Zhan, Li, Yang, Feng, Zhang, Zhang, Zhao and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of XSEC+EE on guidance factor in MACO rats. The representative image and western-blot analysis for Netrin-1/DCC (A) and Slit-2/Robo-1 (C) were showed on the left. The mRNA of Netrin-1/DCC (B) and Slit-2/Robo-1 (D) was determined by RT-PCR analysis. The protein level of Netrin-1/DCC and Slit-2/Robo-1 was quantified using GAPDH as the loading controls. Data are expressed as means ± SE, n = 4 for each group. ^∗∗P < 0.01 and ^∗∗∗P < 0.001 vs. vehicle; ^∧∧P < 0.01 vs. XSEC+EE.