Table 1.
Overview of clinical studies in head and neck cancer patients with MRI before radiotherapy (pre) and at least one additional MR measurement during (mid) or post-radiotherapy (post).
| Author, year | Tumor localization | N | T | MR Sequence | OAR | MRI |
||
|---|---|---|---|---|---|---|---|---|
| pre | mid | post | ||||||
| Marzi, 2018 [8] | OP | 40 | 1.5 | IVIM, DCE | SG | x | x | x |
| Zhou, 2018 [9] | NP | 28 (19)* | 3.0 | T2mapping, mDIXON Quant | SG | x | x | x |
| Zhang, 2018 [10] | NP | 26 | 3.0 | DWI | SG | x | x | x |
| Meheissen, 2018 [11] | OP | 46 | 3.0 | T1, T2, T1c | MS | x | x | x |
| Zhou, 2017 [12] | NP | 26 | 3.0 | T1rho | SG | x | x | x |
| Loimu, 2017 [13] | OP, L | 20 | 1.5 | DWI | SG | x | x | |
| Hatakeyama, 2017 [14] | OP | 39 | 1.5/3.0 | T1, T2 | Bone | x | x | |
| Messer, 2016 [15] | NP | 72 | 1.5 | T1, T2 | MS | x | x | |
| Sandulache, 2016 [16] | OP | 32 | 3.0 | DCE | Bone | x | x | x |
| Marzi, 2015 [17] | OP, NP, HP, L | 34 | 1.5 | IVIM | SG | x | x | x |
| Juan, 2015 [18] | NP | 11 | 1.5 | DWI | SG | x | x | |
| Doornaert, 2014 [19] | OP, HP | 8 | 1.5 | DWI | SG | x | x | x |
| Zhang, 2013 [20] | NP | 28 | 3.0 | DWI | SG | |||
| Ou, 2013 [21] | NP | 14 | 3.0 | MR sialography | SG | x | x | |
| Cheng, 2013 [22] | NP | 16 | 1.5 | DCE | SG | x | x | |
| Houweling, 2011 [23] | OP | 18 | 3.0 | T1, T2, DCE | SG | x | x | |
| Lee, 2011 [24] | NP | 21 | 1.5 | DCE | SG | x | x | |
| Kan, 2010 [25] | OP, NP, HP, L, PS, UP | 14 | 1.5 | T2 | SG | x | x | x |
| Popovtzer, 2009 [26] | OP, NP, HP, UP | 12 | 3.0 | T1, T2 | MS | x | x | |
| Dirix, 2008 [27] | OP, OC, UP | 8 | 1.5 | DWI | SG | x | x | |
| Astreinidou, 2007 [28] | OP, NP | 9 | 1.5 | MR sialography | SG | x | (x) | (x) |
*
28 patients with repetitive T2, 18 patients with repetitive DIXON. DCE: dynamic contrast enhanced imaging, DWI: diffusion weighted imaging, HP: hypopharynx, IVIM: intravoxel incoherent motion imaging, L: larynx, MS: musculoskeletal, NP: nasopharynx, OAR: organ at risk, OC: oral cavity, OP: oropharynx, PS: paranasal sinus, SG: salivary gland, T: magnetic field strength in Tesla, T1c: T1 post contrast, UP: unknown primary.