Table 2.

Changes in T1/T2 MRI of salivary glands during the course of radiotherapy.

Author, year	OAR	Timepoint	Main findings
Zhou, 2018 [9]	PG	BL 5w after RT-start 4w post-RT	T2 values sign. Increase from BL to mid-RT (+6%) and post-RT (+11%). No sign. correlation between dT2 and mean RT dose.
Zhou, 2017 [12]	PG	BL 5w after RT-start 4w post-RT	T1rho sign. increases from BL to mid-RT (+21%) and post-RT (+29%), No sign. correlation of change in T1rho with dose or xerostomia.
Houweling, 2011 [23]	PG, SMG	BL 6w post-RT	Sign increase post-RT in T2 SI (+13%/+29%) and sign. decrease in T1 SI (−8%/−11%) in both SG. Sign. Correlation between change in T2 SI and dose.

BL: baseline, OAR: organ at risk, PG: parotid gland, RT: radiotherapy, SG: salivary gland, SI: signal intensity, sign.: significant/ly, SIR: signal intensity ratio, SMG: submandibular gland, w: week.