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. 2019 Apr 28;7(2):18. doi: 10.3390/proteomes7020018

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Proteomics profiling of vesicles purified from human serum. (A) Numbers of proteins identified in fractions F7 and F9; marked is a subset of “background” proteins detected in unfractionated serum. (B) GO terms associated with the most numerous groups of proteins detected in fraction F7 (173 proteins, background serum proteins excluded); showed are numbers of associated proteins. (C) Clusters of GO terms associated with proteins specific for F7 (92 proteins) and F9 (73 proteins); showed is a percentage of proteins associated with a cluster (F9 vs. F7) and relative enrichment of each protein subset in a given cluster represented by horizontal bars (asterisks marked statistically significant differences; p < 0.05).