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A schematic diagram depicting exosome and microvesicle generation and EV-mediated cell–cell communications. Exosomes are secreted upon fusion of multivesicular endosomes with the cell surface. Microvesicles are generated by the outward budding and fission of the cell membrane. Both exosomes and microvesicles can transfer their cargos from donor cells to recipient cells and consequently modulate recipient cell function.
