Skip to main content
. 2019 May 30;11(6):497. doi: 10.3390/v11060497

Figure 2.

Figure 2

Schematic representations of the major functional domains and comparison of representative Avian Sarcoma and Leukosis Virus (ASLV) subgroups A to E envelope glycoprotein sequences. The envelope glycoprotein leader sequence (Leader), surface glycoprotein sequence (SU), transmembrane glycoprotein sequence (TM) are indicated. The variable region (vr1, vr2, and vr3) and the host range region (hr1 and hr2) sequences in the surface glycoprotein, and the fusion peptide (FP), heptad repeat (HR1 and HR2), and the membrane spanning domain (MSD) sequences in the transmembrane glycoprotein are indicated. The cysteine residues are highlighted in red boxes; the one unpaired cysteine residue at position 100 is highlighted with a blue box. The sequence alignments were done using the ClustalW program in MacVector 14.5.3: identical residues are shaded; conserved residue differences are in boxes, and nonconserved residue differences are unmarked. SR-A: Schmidt–Ruppin A subgroup A ASLV strain UniProt P03397; SR-B: Schmidt–Ruppin B subgroup B ASLV Genbank AAC08989; RAV-2, this study and Genbank AAA87241; Prague-C subgroup C ASLV Genbank AAB59934.1; SR-D: Schmidt–Ruppin D subgroup D ASLV Genbank BAD98245.1; RAV-0* is a partial sequence of a subgroup E ASLV and is the combination of two partial sequences: Genbank AAA87242 and CAA30677.