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. 2019 Jun 25;24(12):2344. doi: 10.3390/molecules24122344

Figure 5.

Figure 5

Effect of KWM-EO on the inflammatory immune system in skin tissue from the mice two-stage skin carcinogenesis. Immunofluorescent staining of inflammatory mediator COX-2 (red) with neutrophil elastase (green) (A) and macrophage marker, F4/80 (green) (B). Nuclei were counterstained with DAPI (blue). Representative images are shown. The data are representative of three independent experiments and are expressed as mean ± SD. N.S. means non significance; P* < 0.05, P** < 0.01, P*** < 0.001 compared to DT group; P## < 0.01, P### < 0.001 compared to DTP group (ANOVA). Scale bar: 100 μm.