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. 2019 Jun 23;7(2):35. doi: 10.3390/toxics7020035

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Diabetic incidence, blood glucose levels (BGLs), glucose tolerance tests (GTT) and insulin tolerance tests (ITT) in female non-obese diabetic (NOD) mice on the soy-based diet. (A) Type 1 diabetes (T1D) incidence (N = 5–6). Blood glucose ≥250 mg/dL was considered diabetic. (B) Time course of non-fasting BGLs. Also shown are GTTs after 1 month (C) and 2 months (D) of BPS exposure (N = 5–6), and ITTs after 1 month (E; N = 5–6) and 2 month (F; N = 3–5) of BPS exposure. The values are presented as mean ± SEM. *, p < 0.05 for 30 μg/kg BPS vs. vehicle (VHF) control group. ^#, p < 0.05 for 3 μg/kg BPS vs. VHF group. ^†, p < 0.05 for 300 μg/kg BPS vs. VHF group.