Table 3.

mRNA expression of TRPV1 and TRPA1 in the animal colon (ISH: in situ hybridization).

mRNA	Location	Method	Model, Animal Species/Strain	Ref
TRPV1	isolated crypts, submucosal and muscle layers of distal, middle and proximal colon	qPCR	intact male Wistar rats	[54]
	upregulated in colonic DRG to the distal colon in DSS-colitis		2.5% DSS-treated C57BL/6 mice	[51]
	unaltered in distal colon, cell type not specified		DSS colitis - male C57BL/6 mice	[33]
	CD4+ T cells		primary cell culture from C57BL/6 spleen	[55]
TRPA1	muscularis externa and mucosa of duodenum, ileum and colon; cell type not specified		intact C57BL/6 mice	[53]
	surface epithelium of middle colon	ISH	intact male Wistar rats	[54]
	isolated crypts, submucosal and muscle layers of distal, middle and proximal colon	qPCR	intact male Wistar rats	[54]
	upregulated in distal colon, cell type not specified		DSS colitis - male C57BL/6 mice	[33]