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. 2019 Mar 31;4(2):57. doi: 10.3390/tropicalmed4020057

Table 1.

Demographic and clinical characteristics of the study population.

Characteristic Frequency (%) Non-TB (n = 182) SPCP (n = 112) SNCP (n = 100) p Value
Age group 0.016
18–24 years 22 (14) 35 (31) 19 (19)
25–35 years 43 (28) 25 (22) 24 (24)
36–45 years 39 (25) 29 (26) 32 (32)
46 years and older 52 (33) 23 (21) 25 (25)
Age in years: Mean (SD) 40 (15) 34 (11) 37 (37) 0.005
Male 79 (51) 87 (74) 68 (68) <0.001 *
Cigarette Smoker 42 (27) 61 (54) 35 (35) <0.001 *
Country **
Viet Nam 72 (40) 71 (58) 40 (40)
South Africa 110 (60) 51 (42) 60 (60)
Alcohol consumption 0.008
No 88 (72) 50 (47) 51 (61)
Less 25 (20) 41 (38) 19 (23)
Weekly 6 (5) 10 (9) 12 (14)
Daily 3 (2) 6 (6) 2 (2)
Frequent to intoxication 2 (2) 2 (2) 1 (1)
HIV positive ** 50 (27) 49 (40) 50 (50)
Clinical symptoms and Medical History
Cough duration <0.001 *
1–4 weeks 97 (78) 52 (48) 55 (71)
5–10 weeks 17 (14) 33 (30) 15 (19)
11 weeks or longer 10 (8) 24 (22) 7 (9)
Cough duration (weeks): Mean (SD) 7 (28) 10 (18) 5 (5) <0.001 *
Expectoration 93 (98) 66 (97) 51 (94) 0.512
Haemoptysis 19 (12) 16 (14) 15 (15) 0.773
Dsypnea 62 (40) 44 (39) 53 (53) 0.068
Night sweats 88 (56) 70 (63) 68 (69) 0.141
Weight loss 95 (61) 78 (70) 70 (71) 0.178
Fever above 38 °C 76 (49) 74 (66) 67 (68) 0.002 *
Chest pain 79 (51) 65 (58) 66 (67) 0.041
Malaise 95 (61) 73 (65) 70 (71) 0.277
Wasting 12 (8) 21 (19) 28 (28) <0.001 *
Enlarged lymph nodes 1 (1) 5 (5) 5 (6) 0.107
Abnormal chest x-ray 96 (64) 116 (98) 83 (92) <0.001 *
Chest x-ray interpretation 0.011
Infiltrate or consolidated 70 (76) 74 (65) 52 (63)
Pleural effusion 1 (1) 2 (2) 4 (5)
Cavitary lesion 2 (2) 20 (18) 9 (11)
Tuberculoma 0 (0) 0 (0) 1 (1)
Mediastinal/hilar lymphoadenopathy 5 (5) 3 (3) 5 (6)
Micronodules (Miliar) 0 (0) 5 (4) 3 (4)
Other 14 (15) 9 (8) 8 (10)
Chest x-ray conclusion <0.001 *
TB likely 15 (16) 114 (98) 64 (77)
Pneumonia or atypical TB 35 (36) 1 (1) 16 (19)
Pneumonia (TB unlikely) 27 (28) 0 (0) 0 (0)
Other 19 (20) 1 (1) 3 (4)
Contact with active TB case 27 (17) 21 (19) 27 (27) 0.142
BCG vaccinated 81 (63) 63 (67) 62 (67) 0.757
Previous TB 36 (23) 13 (11) 21 (22) 0.029
General appearance 0.004
Not ill 41 (26) 13 (12) 13 (13)
Mildly ill 68 (44) 47 (42) 51 (51)
Moderately/gravely ill 47 (30) 52 (46) 36 (36)

Note: Patient diagnosis confirmed with culture (C) and sputum smear microscopy (SS) with follow-up at two months. Statistical comparisons were conducted using Kruskal-Wallis for numerical variables and Pearson chi-square tests for binomial/categorical variables, two-tailed. * p values < 0.002 (Bonferonni adjusted) are significant. ** Human immunodeficiency virus (HIV) and country were pre-determined during sample selection, hence not statistically compared.