Table 2.
A comparison of thiol/disulphide and other oxidative stress parameters in Graves’ patients and the control group.
| Data | Control (n = 35) | Graves (n = 33) | p-Values |
|---|---|---|---|
| Native thiol (mmol/L) | 454.95 ± 57.89 | 397.42 ± 51.26 | <0.001 |
| Total thiol (mmol/L) | 489.79 ± 58.05 | 439.47 ± 42.02 | <0.001 |
| Disulphide (mmol/L) | 17.42 ± 6.67 | 21.03 ± 9.10 | 0.066 |
| Disulphide/Native thiol (%) | 3.92 ± 1.62 | 5.56 ± 2.81 | 0.004 |
| Disulphide/Total thiol (%) | 3.59 ± 1.38 | 4.89 ± 2.28 | 0.006 |
| Native thiol/Total thiol (%) | 92.82 ± 2.77 | 90.22 ± 4.56 | 0.006 |
| TAS (mmol TroloxEqv/L) | 0.60 ± 0.15 | 0.55 ± 0.15 | 0,198 |
| TOS (µmol H2O2 Eqv/L) | 1.95 ± 0.44 | 2.40 ± 0.34 | <0.001 |
| OSI (Arbitrary Unite) | 3.47 ± 1.27 | 4.65 ± 1.46 | 0.001 |
| PC (nmol/mg protein) | 2.09 ± 0.49 | 2.52 ± 0.56 | 0.001 |
| 8-OHdG (ng/mL) | 24.52 ± 3.35 | 23.66 ± 3.21 | 0.282 |
TAS, total antioxidant status; TOS, total oxidant status; OSI, oxidative stress index; PC, protein carbonyl; 8-OHdG, 8-Hydroxy-2-deoxyguanosine.