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. 2019 Jun 10;11(6):269. doi: 10.3390/pharmaceutics11060269

Table 2.

Drug load and loading efficiency of Felodipine and Furosimide in mesoporous silica Syloid XDP 3050 with the incorporation of HPMCAS.

% of Theoretical Surface Coverage Felodipine-Syloid-HPMCAS Furosemide-Syloid-HPMCAS
Theoretical Drug Load (%, g/g) Actual Drug Load (%, g/g) Loading Efficiency (%) Theoretical Drug Load (%, g/g) Actual Drug Load (%, g/g) Loading Efficiency (%)
100% 12.6 13.1 ± 0.2 104.0 ± 1.6 10.8 10.7 ± 0.6 99.1 ± 5.5
200% 25.2 20.3 ± 0.5 80.6 ± 1.9 21.6 14.7 ± 1.3 68.1 ± 6.0
300% 37.8 30.3 ± 0.2 80.2 ± 0.5 32.4 23.8 ± 0.6 73.5 ± 1.9