Skip to main content
editorial
. 2019 Jun 14;7(2):42. doi: 10.3390/diseases7020042

Table 1.

Key pathways of epigenetic regulation.

Pathway Mechanism of Action Examples of Impacted Conditions
DNA Methylation DNA–protein interactions embryonic development; epigenetic inheritance; genomic stability; allele-specific expression; inactivation of the X chromosome;
Histone Modifications post-translational modifications of histone tails gene expression; cell cycle regulation; DNA replication; DNA repair; chromatin structure
ATP-Dependent Chromatin Modifications chromatin remodeling complexes containing an ATPase domain cell differentiation; gene expression; cell cycle regulation; DNA replication; DNA repair; chromatin structure
Non-Coding RNA RNA-targeting of CpG islands; small interfering RNAs gene expression