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. 2019 May 22;12(2):79. doi: 10.3390/ph12020079

Figure 2.

Figure 2

Structures of (A) the TAPI-2 affinity resin and (B) the batimastat affinity resin used to capture active MMPs and related ADAMs (a disintegrin and metalloproteinase). The portion of the structure based on TAPI-2 is indicated in red and that based on batimastat is shown in blue. (C) Recovery of representative active MMPs and ADAMs by the batimastat affinity resin. Mouse tissue homogenate was spiked with 10 pmol of proteinase and incubated with the resin. Recovery was determined from quantitation of the proteinase recovered after the clean-up procedure relative to the spiked amount; mean ± SD, n = 3.