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. 2019 Jun 22;24(12):2316. doi: 10.3390/molecules24122316

Figure 4.

Figure 4

Modulation of the formation of toxic Aβ oligomers by polyphenols. Resveratrol enhances the clearance of Aβ monomer. Rosmarinic acid and curcumin directly inhibit oligomerization by interfering with peptide–peptide interactions while resveratrol and EGCG remodel toxic Aβ oligomers to nontoxic assemblies.