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. 2019 Jun 3;55(6):239. doi: 10.3390/medicina55060239

Figure 4.

Figure 4

Transmission electron photomicrographs showing similar morphological stages of mitochondrial vacuolar degeneration in cardiac myocytes overexpressing BNIP3 (A) and constitutively active FOXO3a (B). Blue arrows pointing at mitochondrion at a specific stage of mitochondrial vacuolar degeneration. Black arrows pointing at autophagosomes. Zoomed photomicrograph in A, showing an autophagosome containing a fragmented mitochondrion fusing with a lysosome. L: lysosome. Photomicrographs are 40k × magnified, scale bar 0.5 μm.