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. 2019 Jul 11;178(2):374–384.e15. doi: 10.1016/j.cell.2019.05.055

Figure 7.

Figure 7

SJs Reversibly Gate Cell-Cell Communication by a Conformational Change

SJs (green, open; orange, closed) of Anabaena are dynamic, gated cell-cell connections, which reversibly block intercellular molecular diffusion along the filament upon different types of stress. The ΔfraD mutant was missing the cap and plug modules, consistent with the inability to close SJs upon stress. FraD was shown to localize to the plug module.

See also Figure S7.