Table 3.
Antibodies undergoing clinical trials.
| Antibody | Target/Mechanism of Action | Clinical Phase Status | Country |
|---|---|---|---|
| MEDI8852 | HA stem | IIa completed | USA |
| MHAA4549A | HA stem | II completed | USA |
| VIS410 | HA stem | II completed | USA |
| Intravenous hyper-immune immunoglobulin (IVIG) | Antigen specific antibody pool with neutralizing potential | III recruiting | USA |
| Ergoferon | Suppression of non-specific immune activation (by any virus) | IV completed | Russia |
| CR6261 | “highly conserved membrane-proximal stem of H1 and H5 viruses’ HA1 and HA2” | II completed | USA |
Note: Information was retrieved from the clinicaltrials.gov.