Schematic presentation of oxidation and antioxidant pathways in chronic kidney disease. NADPH, nicotinamideadenine dinucleotide phosphate; SOD, superoxide dismutase; NOS, nitric oxide synthase; CytP450, cytochromes P450; GSH, reduced glutathione; GSSG, oxidized glutathione; GSH-PX, glutathione peroxidase.