Table 1.
Characterization of the functionalized alginates in this study: P0 = mole periodate per mole uronate residue), degree of substitution (DS, mole substituent per mole uronate residue%), average molecular weight (Mw). POA: Oxidized alginate. POA-MeOTyr: Oxidized alginate grafted with methyl tyrosine ester. POA-β-CyD: Oxidized alginate grafted with beta cyclodextrin, POA-GRGDSP: Oxidized alginate grafted with the hexapeptide GRGDSP. Epim POA-MeOTyr: oxidized mannuronan grafted with methyl tyrosine ester and, thereafter, epimerized to a G-content of 49%.
| Material | P0 | DS (%) | Mw (kDa) |
|---|---|---|---|
| L. hyperborea stipe alginate | 0.00 | - | 133 |
| POA | 0.02 | - | 99 |
| POA | 0.04 | - | 93 |
| POA | 0.08 | - | 97 |
| POA-MeOTyr | 0.08 | 7.0 | 114 |
| POA-β-CyD | 0.08 | 1.6 | 65 |
| POA-GRGDSP | 0.08 | 3.9 | 134 |
| Epim POA-MeOTyr | 0.08 | 7.9 | 126 |